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A Convenient New Synthesis of Fused 1,2,4-Triazoles: The Oxidation of Heterocyclic Hydrazones Using Copper Dichloride.

✍ Scribed by Michael Ciesielski; Daniela Pufky; Manfred Doering

Publisher
John Wiley and Sons
Year
2005
Weight
24 KB
Volume
36
Category
Article
ISSN
0931-7597

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The Use of Copper Flow Reactor Technolog
The Use of Copper Flow Reactor Technology for the Continuous Synthesis of 1,4-Disubstituted 1,2,3-Triazoles
✍ Andrew R. Bogdan; Neal W. Sach 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 276 KB 👁 2 views

## Abstract magnified image A library of 1,4‐disubstituted 1,2,3‐triazoles was synthesized using a copper flow reactor. Organic azides, generated __in situ__ from alkyl halides and sodium azide, were reacted with acetylenes using the copper‐catalyzed Huisgen 1,3‐dipolar cycloaddition. This process