Our interest in the intramolecular cycloaddition of nitrile oxides with olefins as a tool for natural product synthesis prompts this report of a simple one-pot synthesis of nitroalkanes from aldehydes. Nitroalkanes are useful precursors to these dipolar intermediates. 1 Further, the considerable pr
✦ LIBER ✦
A convenient method for preparing α-halogenated nitroalkanes
✍ Scribed by A. L. Fridman; V. P. Ivshin; T. N. Ivshina; S. S. Novikov
- Book ID
- 112433040
- Publisher
- Springer
- Year
- 1969
- Tongue
- English
- Weight
- 164 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1573-9171
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The first synthesis of diazoesters by direct diazotization of amino acid esters was reported by Curtius I,\*) around 1900. Although this method is well suited for the preparation of diazoacetic ester, 3) it is generally inapplicable to the syntheses of a-substituted-a-diazoesters (I),\*) because of