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A convenient approach towards 2′-analogs of zoapatanol from d-glucose

✍ Scribed by Huib Ovaa; Gijs A van der Marel; Jacques H van Boom

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
94 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

The protected 3-C-methyl-a-D-allofuranose derivative 6, readily accessible from D-glucose, could be transformed into a diene scaffold which underwent ring-closing metathesis (RCM) to give the functionalized oxepines 10a,b. Further elaboration of 10a,b provided the 2%-zoapatanol analogs 3-5.

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