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Immobilized glucose oxidase and d-amino acid oxidase: A convenient method for the purification of flavin adenine dinucleotide and its analogs

✍ Scribed by Vincent Massey; Loren D. Mendelsohn


Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
330 KB
Volume
95
Category
Article
ISSN
0003-2697

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✦ Synopsis


The preparation of flavin adenine dinucleotide-aftinity columns employing glucose oxidase and D-amino acid oxidase covalently linked to Sepharose-4B is described. Both immobilized enzymes have very good long-term stabilities, retaining at least half of their original flavin adenine dinucleotide-binding capacity over 11 months. In both cases pure flavin adenine dinucleotide is obtained readily in good yields.