The major product from the alkylation of thexyldialkylalkynylborates is the vinylborane in which the groups derived from the alkylating agent and from migration from boron to carbon are cis to each other. -We have recently defined conditions for the alkylation of trialkylalkynylborates (VI) leading
A Consecutive Approach Towards the Stereoselective Synthesis of Trisubstituted THF Domains.
β Scribed by Ram Sagar; L. Vijaya Raghava Reddy; Mohammad Saquib; Brijesh Kumar; Arun K. Shaw
- Book ID
- 102001231
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 22 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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A highly stereoselective synthesis of a tetracyclic intermediate 2 to the quinone antitumor antibiotic naphthyridinomycin I\_ is described.
A highly efficient synthesis of a tetracyclic intermediate 2 to the antitumor antibiotics AX-2 4, mitomycin A 2, and C \_l\_ is described. Mitomycin C 1 is one of the most effective antitumor agents currently used for chemotherapy.1