A Conformational Study of Two Cyclic Peptide Analogues of α-MSH
✍ Scribed by GEORGE FORSYTH; SARAH BRANCH; STEPHEN MOSS; LIDIA NOTARIANNI; DAVID OSGUTHORPE; COLIN POUTON
- Book ID
- 119868420
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 142 KB
- Volume
- 680
- Category
- Article
- ISSN
- 0890-6564
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
We have solved the crystal structures of nine pseudo-peptide analogues deriving from the hydrazino analogue of glycine or valine (NBH2-N"H-C"HR-C02H, R = H or i P r ) or proline ( NBH2-N"-C"H-C02H) and containing the hydrazide ( CO-NOH-N" <) or N@-Z-aminoamide [ CO-N"( NBHZ)] peptidomimetic link. Th
bonds have been carried out in different solvents to investigate the formation and stabilization of @-turn structures and to determine the stereochemistry of the disulfide linkage. Both peptides have three-dimensional structures with a type I1 P-turn, as derived from quantitative nuclear Overhauser