New C-4 thiazole 4, 5 and aminothiazole 6, 7 kainoid analogues were efficiently synthesised in five steps from commercially available (-)-alpha-kainic acid I and exhibited strong binding to the kainate receptors. A reactive alpha-bromoketone 10 was generated and reacted with thioamides and thioureas
β¦ LIBER β¦
A concise approach to kainoid analogues
β Scribed by Jack E. Baldwin; Martin Rudolph
- Book ID
- 103406952
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 227 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0040-4039
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