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A Concise and Flexible Synthesis of the Potent Anti-Influenza Agents Tamiflu and Tamiphosphor

โœ Scribed by Jiun-Jie Shie; Jim-Min Fang; Chi-Huey Wong

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
316 KB
Volume
47
Category
Article
ISSN
0044-8249

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Through the synthesis of authentic samples, we have now determined that the major by-product arising from the conversion 4?5 is the PMB ether of m-bromophenol (A) and not the PMB ether of the corresponding o-isomer (B) as originally stated.