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A Concept for Synthesis Planning in Solid-State Chemistry

โœ Scribed by Martin Jansen


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
594 KB
Volume
41
Category
Article
ISSN
0044-8249

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โœ Stephen R. Byrn; George Zografi; Xiaoming (Sean) Chen ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 304 KB

In this perspective we have shown that the process of ''proof of concept'' (POC) in the early part of drug development can be greatly accelerated by close attention to the underlying solid-state chemistry (SSC) of a new chemical entity. POC seeks data that provide confidence in the therapeutic activ