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A Concept for Synthesis Planning in Solid-State Chemistry

โœ Scribed by Martin Jansen

Publisher
John Wiley and Sons
Year
2003
Weight
69 KB
Volume
34
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

๐Ÿ“œ SIMILAR VOLUMES

Accelerating proof of concept for small
Accelerating proof of concept for small molecule drugs using solid-state chemistry
โœ Stephen R. Byrn; George Zografi; Xiaoming (Sean) Chen ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 304 KB

In this perspective we have shown that the process of ''proof of concept'' (POC) in the early part of drug development can be greatly accelerated by close attention to the underlying solid-state chemistry (SSC) of a new chemical entity. POC seeks data that provide confidence in the therapeutic activ