A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE®Bone Graft)
✍ Scribed by William F. McKay; Steven M. Peckham; Jeffrey M. Badura
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 240 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0341-2695
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Recombinant human bone morphogenetic protein-2 (rhBMP-2) is known to induce orthotopic and ectopic bone formation in vivo. Several in vitro studies using rat or mouse clonal cell lines have shown that rhBMP-2 may be involved in the differentiation of osteoblasts from osteoblast precursor cells or st
To determine if recombinant human bone morphogenetic protein-2 (rhBMP-2) can be adsorbed onto porous ceramic hydroxyapatite (HA) and promote the integration of HA to host bone, 54 subperiosteal pockets were created on the skulls of 19 adult Pasteurella-free white rabbits. Fourteen HA implants were s
## Abstract Bone morphogenetic protein (BMP)‐2 plays an important role in bone growth and regeneration; however, BMP‐2 is easily lost by diffusion through body fluid and has some inhibitory pathways. To address this problem, we previously immobilized recombinant human BMP‐2 (rhBMP‐2) on succinylate