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A Comparison of the Effect of the 3-Hydroxy-3-Methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitors Simvastatin, Lovastatin and Pravastatin on Leukaemic and Normal Bone Marrow Progenitors

โœ Scribed by Newman, Ann; Clutterbuck, Robyn; Powles, Ray; Catovsky, Daniel; Millar, John


Book ID
118238643
Publisher
Informa plc
Year
1997
Tongue
English
Weight
325 KB
Volume
24
Category
Article
ISSN
1042-8194

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๐Ÿ“œ SIMILAR VOLUMES


Relative lipophilicities, solubilities,
โœ Abu T. M. Serajuddin; Sunanda A. Ranadive; Eileen M. Mahoney ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 532 KB

The apparent octanol-water partition coefficients (Po/w) and aqueous solubilities for four 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors [pravastatin, lovastatin (mevinolin), mevastatin (compactin), and simvastatin (synvinolin)] were compared. Pravastatin is highly hydrophilic