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The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells

โœ Scribed by Sharon A Glynn; Dermot O'Sullivan; Alex J Eustace; Martin Clynes; Norma O'Donovan


Book ID
115011505
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
353 KB
Volume
8
Category
Article
ISSN
1471-2407

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๐Ÿ“œ SIMILAR VOLUMES


Relative lipophilicities, solubilities,
โœ Abu T. M. Serajuddin; Sunanda A. Ranadive; Eileen M. Mahoney ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 532 KB

The apparent octanol-water partition coefficients (Po/w) and aqueous solubilities for four 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors [pravastatin, lovastatin (mevinolin), mevastatin (compactin), and simvastatin (synvinolin)] were compared. Pravastatin is highly hydrophilic