A Comparison of Dichloralphenazone and Chloral Hydrate*
β Scribed by Rice, W.B. ;McColl, J.D.
- Publisher
- Elsevier
- Year
- 1956
- Weight
- 483 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0095-9553
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Chloralβ1,2β^14^C hydrate was prepared by direct chlorination of labeled acetaldehyde in an overall 47% radiochemical yield. The reaction was carried out without a catalyst by heating at one temperature in a single stage reaction. No lower chloroacetaldehydes were detected.
The subchronic toxicity of chloral hydrate, a disinfection byproduct, was studied in rats following 13 weeks of drinking water exposure. Male (262 +/- 10 g) and female (190 +/- 8 g) Sprague-Dawley rats, ten animals per group, were administered chloral hydrate via drinking water at 0.2, 2, 20 and 200