A comparison of cyclophosphamide therapy with 6-mercaptopurine therapy in children with untreated acute leukemia
β Scribed by D.J. Fernbach; M.E. Haggard; T.M. Holcomb; J. Windmiller; T.J. Vietti; W.W. Sutow; K.M. Griffith
- Book ID
- 118534330
- Publisher
- Elsevier Science
- Year
- 1965
- Tongue
- English
- Weight
- 66 KB
- Volume
- 67
- Category
- Article
- ISSN
- 1097-6833
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π SIMILAR VOLUMES
Intraindividual variation in 6-mercaptopurine (6-MP) kinetics has been little studied. It has now been examined in 18 children with acute lymphoblastic leukaemia (ALL). On 2 to 4 occasions in each patient drug concentrations in plasma and red cells were followed for 4 h after administration by means
A randomized study of methotrexate vs. 6-mercaptopurine and prednisone was carried out in 45 previously untreated patients with acute leukemia. Methotrexate was given orally in divided daily doses for 5-day courses a t intervals of ten to 14 days. Six-mercaptopurine and prednisone were given daily u