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A comparison of covalent DNA binding of benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in respiratory tissues from human, rat and mouse

✍ Scribed by Stoner, Gary D.; Schut, Herman A.J.; Daniel, F.Bernard; Dixit, Rakesh


Book ID
122783872
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
810 KB
Volume
30
Category
Article
ISSN
0304-3835

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Reaction of 7,12-dimethylbenz(a)anthrace
✍ Gerhard Doerjer; Helga Diessner; Joachim Bücheler; Paul Kleihues 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 French ⚖ 374 KB

## Abstract Pregnant BD‐IX rats (21st day of gestation) received a single IV injection (15 mg/kg) of tritiated 7,12‐dimethylbenz(__a__)anthracene (DMBA), a dose known to induce a high incidence of nervous‐system tumors in the offspring. The animals were killed 12 h later and hydrocarbon‐deoxyribonu