## Abstract ## Objective To quantify the levels of proteoglycan 4 (PRG4) expression by subpopulations of chondrocytes from superficial, middle, and deep layers of normal bovine calf cartilage in various culture systems. ## Methods Bovine calf articular cartilage discs or isolated cells were used
A comparison of chondrocyte proteoglycan metabolism in monolayer and agarose cultures
✍ Scribed by S. Spirito; R. L. Goldberg; G. Di Pasquale
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1993
- Tongue
- English
- Weight
- 193 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1420-908X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Interleukin-6 (IL-6) levels are markedly increased in the synovial fluid of patients with rheumatoid arthritis or osteoarthritis. However, the effects of IL-6 on proliferation and proteoglycan metabolism in articular cartilage are not known. We demonstrated here the effects of human recombinant (hr)
Chondrocytes in vivo show distinct characteristics related to their structure and function. These in- clude an extracellular accumulation of proteoglycans and a specific type of collagen characteristic of articular cartilage, designated as [c~,(11)]~. These substances constitute the major macromolec
## Abstract ## Objective To investigate the effect of isolated hydrostatic pressure on proteoglycan metabolism in chondrocytes. ## Methods Bovine articular chondrocytes cultured in agarose gels were subjected to 5 MPa hydrostatic pressure for 4 hours in either a static or a pulsatile (1 Hz) mode
## Abstract The effect of 3 purified peptide growth factors—platelet‐derived growth factor (PDGF), epidermal growth factor (EGF), pituitary fibroblast growth factor (FGF)—heat‐inactivated fetal bovine serum (FBS), insulin, and 0.2 m__M__ ascorbate on synthesis of sulfated proteoglycan by rabbit art