𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Comparison of Association Methods Correcting for Population Stratification in Case–Control Studies

✍ Scribed by Chengqing Wu; Andrew DeWan; Josephine Hoh; Zuoheng Wang

Book ID
111111613
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
135 KB
Volume
75
Category
Article
ISSN
0003-4800

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Centralizing the non-central chi-square:
Centralizing the non-central chi-square: a new method to correct for population stratification in genetic case-control association studies
✍ Prakash Gorroochurn; Gary A. Heiman; Susan E. Hodge; David A. Greenberg 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 249 KB 👁 2 views

## Abstract We present a new method, the δ‐centralization (DC) method, to correct for population stratification (PS) in case‐control association studies. DC works well even when there is a lot of confounding due to PS. The latter causes overdispersion in the usual chi‐square statistics which then h

Genotype-based matching to correct for p
Genotype-based matching to correct for population stratification in large-scale case-control genetic association studies
✍ Weihua Guan; Liming Liang; Michael Boehnke; Gonçalo R. Abecasis 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 316 KB 👁 2 views

## Abstract Genome‐wide association studies are helping to dissect the etiology of complex diseases. Although case‐control association tests are generally more powerful than family‐based association tests, population stratification can lead to spurious disease‐marker association or mask a true asso