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A comparative study of the in vivo behaviour of [18F] 2-, 5- and 6-fluoro-L-dopa in the human brain

✍ Scribed by R. Chirakal; N. Vasdev; G. J. Schrobilgen; S. Amano; C. Nahmias


Book ID
112132884
Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
288 KB
Volume
44
Category
Article
ISSN
0022-2135

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[18F]Fluoro-l-dopa for the in vivo study
✍ Gunter Firnau; E.S. Garnett; Raman Chirakal; Sudesh Sood; Claude Nahmias; Gary S πŸ“‚ Article πŸ“… 1986 πŸ› Elsevier Science βš– 457 KB

6-[18F]Fluoro-L-dopa was designed to trace the dopamine metabolism in the brain with positron tomography. 6-[18F]Fluoro-L-dopa resembles natural L-dopa biochemically, it crosses the blood-brain barrier with the similar kinetics, it is decarboxylated by dopa decarboxylase and is stored intraneuronall