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Production of 6-[18F]fluoro-l-DOPA and its metabolism in vivo—a critical review


Book ID
123594110
Publisher
Elsevier Science
Year
1992
Weight
23 KB
Volume
19
Category
Article
ISSN
0883-2897

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## Abstract Progression of Parkinson's disease symptoms is imperfectly correlated with positron emission tomography biomarkers for dopamine biosynthetic pathways. The radiopharmaceutical 6‐[^18^F]fluoro‐m‐tyrosine is not a substrate for catechol‐__O__‐methyltransferase and therefore has a more favo