✦ LIBER ✦

A community prevalence study of antibodies to hepatitis A and E in inner-city London

✍ Scribed by Bernal, W.; Smith, H.M.; Williams, Roger

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 582 KB
Volume: 49
Category: Article
ISSN: 0146-6615
DOI: 10.1002/(sici)1096-9071(199607)49:3<230::aid-jmv12>3.0.co;2-g

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✦ Synopsis

The seroprevalence of antibodies to hepatitis E virus (HEV) and hepatitis Avirus (HAV) was determined in a community-based sample in innercity London where socioeconomic conditions were expected to result i n a high prevalence of antibodies to HAV, and in which the presence of immigrants from the developing world pose a risk of imported infection of both HAV and HEV. The seroprevalence of anti-HAV was 45.1% in UK born subjects and 69.7% in non-UK born subjects and each group showed differing patterns of agespecific seroprevalence. The seroprevalence rates of anti-HEV was 3.9% in UK born subjects and 8.8% in non-UK born subjects. The age-specific seroprevalence of the UK born group is suggestive of a cohort effect. The data suggest a low circulation of HEV in inner-city London, remaining uncommon relative to HAV.

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