𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Comment on Interim Analyses in Crossover Trials

✍ Scribed by Andrew P. Grieve, Stephen Senn and R. J. Cook


Book ID
125774680
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
713 KB
Volume
52
Category
Article
ISSN
0006-341X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Interim analyses with delayed observatio
✍ Sung C. Choi; Young Jack Lee πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 95 KB πŸ‘ 2 views

The interim analyses based on group sequential procedures are not convenient if the response time relative to the patient accrual rate is long. Since in most trials patients are accrued and randomized continuously, the response data from those already randomized will continue to accumulate when a tr

Multiplicity in randomised trials II: su
✍ Kenneth F Schulz; David A Grimes πŸ“‚ Article πŸ“… 2005 πŸ› The Lancet 🌐 English βš– 185 KB

Subgroup analyses have specious appeal. They seem logical and intuitive-and even fun-to both investigators and readers. However, this insidious appeal causes important problems. Multiplicity and naivetΓ© combine to encourage interpretational missteps in trial conduct and reporting. The subgroup treat