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Predictive checking for Bayesian interim analyses in clinical trials

โœ Scribed by Takashi Daimon


Book ID
116350746
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
517 KB
Volume
29
Category
Article
ISSN
1551-7144

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The interim analyses based on group sequential procedures are not convenient if the response time relative to the patient accrual rate is long. Since in most trials patients are accrued and randomized continuously, the response data from those already randomized will continue to accumulate when a tr