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A colorimetric method for point mutation detection using high-fidelity DNA ligase

✍ Scribed by Li, J.

Book ID
111671252
Publisher
Oxford University Press
Year
2005
Tongue
English
Weight
574 KB
Volume
33
Category
Article
ISSN
0305-1048

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## Abstract The present study reports a proof‐of‐principle for a sensitive genotyping assay approach that can detect single nucleotide polymorphisms (SNPs) based on fluorescence anisotropy measurements through a core–shell fluorescent nanoparticles assembly and ligase reaction. By incorporating the