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A CFSE based assay for measuring CD4+CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses

✍ Scribed by Koen Venken; Marielle Thewissen; Niels Hellings; Veerle Somers; Karen Hensen; Jean-Luc Rummens; Piet Stinissen


Book ID
113717366
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
859 KB
Volume
322
Category
Article
ISSN
0022-1759

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Identification of a CD4+CD25+ T cell sub
✍ Esther N. M. Nolte-‘t Hoen; Josée P. A. Wagenaar-Hilbers; Elmieke P. J. Boot; Ch 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 347 KB 👁 1 views

## Abstract Naturally occurring CD4^+^ regulatory T cells can be identified on the basis of expression of CD25 and suppression of T cell responses __in vitro__ after TCR triggering. Here, we demonstrate that a CD134^+^ subset of CD4^+^CD25^+^ T cells in naive rats suppresses antigen‐specific T cell