A cell line derived from a well-differentiated human transitional cell carcinoma of the urinary bladder, designated TSGH-8301, was established in vitro. The cultured epithelioid cells exhibited monolayer growth and loss of contact inhibition. The tumorigenicity of TSGH-8301 had been shown by growth
A cell line (SCaBER) derived from squamous cell carcinoma of the human urinary bladder
โ Scribed by Carol O'Toole; S. Nayak; Z. Price; W. H. Gilbert; J. Waisman
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- French
- Weight
- 823 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0020-7136
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โฆ Synopsis
Abstract
An established cell line derived from a documented squamous cell carcinoma of human urinary bladder is described. The cultured cells retained the characteristic morphology of the tumor of origin for 40 in vitro passages. Numerous desmosomes were found between cultured cells. Chromosome analysis showed hypotetraploidy with no obvious modal number, while distinctive marker chromosomes and a male karyotype were present.
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