A biogenetically significant cyclization of humulene-4,5-epoxide
โ Scribed by Jerzy A. Mlotkiewicz; Judith Murray-Rust; Peter Murray-Rust; William Parker; Frank G. Riddell; James S. Roberts; Abdul Sattar
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- French
- Weight
- 254 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
Rearrangement of humulene-4,5-epoxide with boron trifluoride etherate leads to the formation of two tricyclic alcohols the structures of which are closely related to that of africanol; the z-ray structure of the E-bromobenzoate of one of the alcohols is reported.
๐ SIMILAR VOLUMES
In the hypothesis of illudoids' biosynthesis2, formation of the key intermediate protoilludyl cation&has been reasonably explained by the cationic cyclization of humulene, initiated at the 4 '\*lo double bond (Scheme I). However,
Recent i n v e s t i g a t i o n s concerning t h e o x i d a t i v e metabolism of b e n z o k lpyrene (Be) have implicated various epoxides as intermediates [l].