A Novel Highly Effective Chiral Lithium
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Masatoshi Asami; Takashi Suga; Kiyoshi Honda; Seiichi Inoue
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Article
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1997
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Elsevier Science
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French
โ 531 KB
A highlyenantioaelectivedeprotonationof meso-epoxideswas achievedby a catalyticamount of a new chiral lithiumamide, derived from (ZS,3aS,7aS)-2-(pyrrolidin-l-ylmethyl)octahydrO indole, in the presenceof excesalithiumdiisopropylamideto afford the correspondingallylic alcoholderivatives up to9470ee. 0