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A biogenetically patterned concept for the laboratory synthesis of cyclic compounds

✍ Scribed by William S. Johnson; Russell A. Bell


Publisher
Elsevier Science
Year
1960
Tongue
French
Weight
281 KB
Volume
1
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES


A biogenetically-patterned laboratory sy
✍ E.E. van Tamelen; L.J. Dolby; R.G. Lawton πŸ“‚ Article πŸ“… 1960 πŸ› Elsevier Science 🌐 French βš– 241 KB

Although the method by which Nature constructs the complex polycyclic structures characteristic of strychnine (I) and related bases (including the curare alkaloid group e.g. C-fluorocurarine, IIlp2) has been the subject of detailed discussion, a,4 no synthesis

General method for the synthesis of cycl
✍ Michael A Walker; Timothy Johnson πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 82 KB

A number of cyclic peptides, wherein the i and i+1 residue side chains are joined by an alkyl linker and a Weinreb amide is present at the C-terminus, were synthesized. Using LiCl to solubilize these peptides in THF the C-terminus can be readily converted to an activated carbonyl such as an aldehyde