๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

General method for the synthesis of cyclic peptidomimetic compounds

โœ Scribed by Michael A Walker; Timothy Johnson

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
82 KB
Volume
42
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis

A number of cyclic peptides, wherein the i and i+1 residue side chains are joined by an alkyl linker and a Weinreb amide is present at the C-terminus, were synthesized. Using LiCl to solubilize these peptides in THF the C-terminus can be readily converted to an activated carbonyl such as an aldehyde or ketone.

๐Ÿ“œ SIMILAR VOLUMES

A new and efficient general method for t
A new and efficient general method for the synthesis of 2-spirobenzopyrans: First synthesis of cyclic analogues of precocene I and related compounds
โœ Suneel Y Dike; Jaysukhlal R Merchant; Niteen Y Sapre ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 569 KB

A new synthesis of spirobenzopyran has been accomplished by Friedel-Crafts reaction of various m-dihydroxybenzenes and cycloalkylidene acetic acid in the presence of a Lewis acid. Chromones, flavones and related heterocyclic compounds belonging to benzopyran family are widely distributed in nature a