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A behavioral assessment of Ts65Dn mice: a putative Down syndrome model

✍ Scribed by Rosa M. Escorihuela; Alberto Fernández-Teruel; Iria F. Vallina; Carmela Baamonde; María A. Lumbreras; Mara Dierssen; Adolf Tobeña; Jesús Flórez

Book ID
116125121
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
528 KB
Volume
199
Category
Article
ISSN
0304-3940

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Motor learning in Ts65Dn mice, a model for Down syndrome
✍ Lynn A. Hyde; Linda S. Crnic; Amber Pollock; Paula C. Bickford 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 152 KB 👁 1 views

Ts65Dn mice are a genetic model for Down syndrome. Both individuals with Down syndrome and Ts65Dn mice have reduced cerebellar volumes and the cerebellum is involved in motor learning. Con¯icting results have been reported on the motor learning abilities of Ts65Dn mice, which may be related to proce