A B cell apotope of Ro 60 in systemic lupus erythematosus
β Scribed by Joanne H. Reed; Michael W. Jackson; Tom P. Gordon
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 163 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Objective B lymphocyte depletion has recently emerged as a promising approach to the treatment of systemic lupus erythematosus (SLE). As part of a phase I/II doseβranging trial of rituximab in the treatment of SLE, we evaluated the fate of discrete B cell subsets in the setting of s
To characterize the initial events in anti-Ro production by a patient with systemic lupus erythematosus, in whom this autoantibody is developing. Methods. The immune response to the Ro ribonucleoprotein and other autoantigens were studied by enzyme-linked immunosorbent assay for IgG and IgM, by iso