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B cell biomarkers of rituximab responses in systemic lupus erythematosus

✍ Scribed by Edward M. Vital; Shouvik Dass; Maya H. Buch; Karen Henshaw; Colin T. Pease; Michael F. Martin; Frederique Ponchel; Andrew C. Rawstron; Paul Emery

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
330 KB
Volume
63
Category
Article
ISSN
0004-3591

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## Abstract ## Objective B lymphocyte depletion has recently emerged as a promising approach to the treatment of systemic lupus erythematosus (SLE). As part of a phase I/II dose‐ranging trial of rituximab in the treatment of SLE, we evaluated the fate of discrete B cell subsets in the setting of s