A new maximal circular code X0(MIT) with two permutated maximal circular codes X1(MIT) and X2(MIT) is identified in the protein coding genes of mitochondria. The three subsets of 20 trinucleotides X0(MIT)={ACA, ACC, ATA, ATC, CTA, CTC, GAA, GAC, GAT, GCA, GCC, GCT, GGA, GGC, GGT, GTA, GTC, GTT, TTA,
A 2006 review of circular codes in genes
β Scribed by Christian J. Michel
- Book ID
- 108077120
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 171 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0898-1221
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π SIMILAR VOLUMES
Recently, shifted periodicities 1 modulo 3 and 2 modulo 3 have been identified in protein (coding) genes of both prokaryotes and eukaryotes with autocorrelation functions analysing eight of 64 trinucleotides (Arquès et al., 1995). This observation suggests that the trinucleotides are associated with
A circular code has been identi"ed in the protein (coding) genes of both eukaryotes and prokaryotes by using a statistical method called trinucleotide frequency (TF) method [Arque`s & Michel (1996). J. theor. Biol. 182, 45}58]. Recently, a probabilistic model based on the nucleotide frequencies with
Several frequency asymmetries unexpectedly observed (e.g. the frequency difference between T 1 and T 2 in the frame 0), are related to a new property of the subset T 0 involving substitutions. An evolutionary analytical model at three parameters ( p, q, t) based on an independent mixing of the 22 co
The subset X0 = [sequence: see text] of 20 trinucleotides has a preferential occurrence in frame 0 (a reading frame established by the ATG start trinucleotide) of protein (coding) genes of both prokaryotes and eukaryotes. This subset X0++ has the rarity property (6 x 10(-8)) to be a complementary ma