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Analysis of a Circular Code Model

✍ Scribed by JÉRÔME LACAN; CHRISTIAN J. MICHEL

Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
277 KB
Volume
213
Category
Article
ISSN
0022-5193

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✦ Synopsis

A circular code has been identi"ed in the protein (coding) genes of both eukaryotes and prokaryotes by using a statistical method called trinucleotide frequency (TF) method [Arque`s & Michel (1996). J. theor. Biol. 182, 45}58]. Recently, a probabilistic model based on the nucleotide frequencies with a hypothesis of absence of correlation between successive bases on a DNA strand, has been proposed by Koch & Lehmann [(1997). J. theor. Biol. 189, 171}174] for constructing some particular circular codes. Their interesting method which we call here nucleotide frequency (NF) method, reveals several limits for constructing the circular code observed with protein genes.

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