## Abstract Full assignments of the ^1^H and ^13^C NMR spectra of clarithromycin (6‐__O__‐methylerythromycin A) in CDCl~3~ and buffered D~2~O were carried out. In contrast to erythromycin A, clarithromycin exists as a single isomer, the 9‐ketone, in aqueous solution.
✦ LIBER ✦
A 1H and 13C NMR study of intramolecular rotations in syn- and anti-o-tolyl-di-tert-butyl-carbinols
✍ Scribed by Bernard Tiffon; John S. Lomas
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 554 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0749-1581
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The complete analysis of the 'H NMR spectra of [ (C,Me,)lr(glycinate)CI] and [ (C,Me,)Ir(N-methyl-g1ycinate)Clj provide information for the conformational analysis of the five-membered N-C-C-0-Ir ring. A Karplus relationship has been established for these metallacycles [ 3J(H,H) = 8.9 cos' 4 -1.0 c