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Structural studies on clarithromycin (6-O-methylerythromycin A): Assignments of the 1H and 13C NMR spectra in organic and aqueous solutions

✍ Scribed by Abida Awan; Jill Barber; Richard J. Brennan; John A. Parkinson

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 479 KB
Volume: 30
Category: Article
ISSN: 0749-1581
DOI: 10.1002/mrc.1260301213

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✦ Synopsis

Abstract

Full assignments of the ^1^H and ^13^C NMR spectra of clarithromycin (6‐O‐methylerythromycin A) in CDCl~3~ and buffered D~2~O were carried out. In contrast to erythromycin A, clarithromycin exists as a single isomer, the 9‐ketone, in aqueous solution.

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