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Structural Aspects of Permethylated Cyclodextrins and Comparison with their Parent Oligosaccharides, as Derived from Unequivocally Assigned 1H and 13C NMR Spectra in Aqueous Solutions

✍ Scribed by Antigone Botsi; Konstantina Yannakopoulou; Eugene Hadjoudis; Bruno Perly


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
466 KB
Volume
34
Category
Article
ISSN
0749-1581

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✦ Synopsis


The complete assignments of the 'H and I3C NMR spectra of a-, /?and y-cyclodextrins (CDs) and their permethylated derivatives were derived from dedicated experiments. Existing literature data were complemented with detailed analyses, including unequivocal assignment of the methoxy groups. The structures of the macrocycles in solution, as derived from the NMR data, resemble those in the solid state. The increased distortions observed for the larger permethylated CDs are expected to affect seriously their complexing ability.