99mTc-EC-Guanine: Synthesis, Biodistribution, and Tumor Imaging in Animals
β Scribed by David J. Yang; Kaoru Ozaki; Chang-Sok Oh; Ali Azhdarinia; Thomas Yang; Megumi Ito; Allison Greenwell; Jerry Bryant; Saady Kohanim; Vincenzo K. Wong; E. Edmund Kim
- Publisher
- Springer US
- Year
- 2005
- Tongue
- English
- Weight
- 698 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0724-8741
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## Abstract The bis(__N__βcyclopentyl dithiocarbamato) nitrido technetiumβ99m complex ^99m^TcN(CPEDTC)~2~ was synthesized by the reduction of ^99m^TcO into [^99m^Tcβ‘N]^2+^ with stannous chloride in the presence of succinic dihydrazide and propylenediamine tetraacetic acid, followed by the addition
Several cationic or neutral technetium-nitrido complexes of Schiff bases [for which 5-methyl 3-(2-hydroxyphenyl methylene) dithiocarbazate (L1) was a prototype], bis-aminoethanethiol (BAT-TM) and macrocyclic amines were prepared. We report here, the synthesis and isolation of these TcNLn complexes f