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952: Frequency of KRAS and NRAS mutations in Bulgarian patients with colorectal cancer

✍ Scribed by Bichev, S.; Andonova, S.; Hristova, L.; Savov, A.


Book ID
125800927
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
69 KB
Volume
50
Category
Article
ISSN
0959-8049

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## Abstract Mutational analysis of __KRAS__ codons 12 and 13 is standard for patients with metastatic colorectal cancer since mutations in these codons predict lack of response to anti‐EGFR therapies. However, even among patients whose tumors are wildtype for __KRAS__ codons 12 and 13, only a subse