9,11-Seco steroids derived from estradiol 3-methyl ether
✍ Scribed by Dygos, John H.; Chinn, Leland J.
- Book ID
- 126793475
- Publisher
- American Chemical Society
- Year
- 1973
- Tongue
- English
- Weight
- 671 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
Reaction of readily available IIR-hydroxy-8B,9-epoxy-steroids with hydrogen fluoride-pyridine gave the corresponding 9.10-seco-derivatives in good yields. Ring cleavages between C-9 and C-IO of steroids by micro-organisms 1) or photo-2)H.H. Inhoffen, Angew. Chem. ;z, 875 (1960). 3)(a) D.
## Abstract The preparation of 9α, 11ζ‐tritiated estrone‐3‐methyl ether with high specific activity is described. The following syntheses gave 17α‐CH~2~X‐derivatives of estradiol (X = CN and SCN) with high specific activity and radiochemical purity higher than 98%. Radiolysis and storage conditions