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Steroids XLI. preparation of 9α, 11ζ-tritiated estrone-3-methyl ether and following syntheses of 17α-CH2X-derivatives of estradiol

✍ Scribed by K. Ponsold; J. Römer; H. Wagner


Book ID
102370433
Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
322 KB
Volume
10
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

The preparation of 9α, 11ζ‐tritiated estrone‐3‐methyl ether with high specific activity is described. The following syntheses gave 17α‐CH~2~X‐derivatives of estradiol (X = CN and SCN) with high specific activity and radiochemical purity higher than 98%. Radiolysis and storage conditions are examined.