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8-Bromination of 2,6,9-trisubstituted purines with pyridinium tribromide

✍ Scribed by Bliman, David; Pettersson, Mariell; Bood, Mattias; Grøtli, Morten


Book ID
121673637
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
434 KB
Volume
55
Category
Article
ISSN
0040-4039

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Solution-phase synthesis of 2,6,9-trisub
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A simple three-step method for the solution-phase combinatorial synthesis of 2,6,9trisubstituted purines from 2,6-dichloropmine is described. The synthesis exploits the use of resin capture to remove excess reagent used in the f'mal step.

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