749 Anti-mitochondrial antibodies in a genetically homogenous population of patients with primary biliary cirrhosis and relatives: the case of Iceland
β Scribed by Sigurdur Olafsson; Hallgrimur Gudjonsson; Carlo Selmi; Katsushi Amano; Pietro Invernizzi; Mauro Podda; M. Eric Gershwin
- Book ID
- 119530655
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 137 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0270-9139
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π SIMILAR VOLUMES
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disorder that can progress to cirrhosis, shortening life expectancy. PBC patients are often asymptomatic, present with biochemical cholestasis, and test positive (>90%) for antimitochondrial antibodies (AMAs) in serum. Although AMA posit
Primary biliary cirrhosis (PBC) is a disease that typically affects middle-aged women and is characterized by progressive intrahepatic cholestasis which leads ultimately to cirrhosis, portal hypertension and hepatocellular failure (1). The underlying histopathological lesion in PBC is a chronic, non