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743 The solution structure of the amyloid β-(1–42) peptide provides a molecular approach for the treatment of Alzheimer's Disease

✍ Scribed by M.G. Zagorski; K.J. Marcinowski; S. Jan; H. Shao; A.R. Salomon; E.L. Clancy; K. Ma; M.H. Lantz; J. Talafous


Book ID
118578190
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
279 KB
Volume
17
Category
Article
ISSN
0197-4580

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✍ Peter P. Mager 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 583 KB

The major protein constituent of the deposits of Alzheimer's disease is the so-called amyloid ␤-peptide (A␤) which was derived from proteolysis of a large transmembrane amyloid precursor protein. Some physicochemical and biological properties of the A␤(1-42) peptide are described in this paper. Thre