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73 Vasculature, perfusion and proliferation in human tumor xenografts and the effect of irradiation with carbogen and nicotinamide

✍ Scribed by Bussink, J.; Kaanders, J.H.A.M.; Rijken, P.F.J.Q.W.; van der Kogel, A.J.


Book ID
122560046
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
144 KB
Volume
40
Category
Article
ISSN
0167-8140

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The goal of this study was to compare, with a human tumor xenograft, two different strategies for increasing tumor response to fractionated irradiation, namely, oxygenating the hypoxic tumor cells with carbogen and nicotinamide, or killing these cells with the hypoxic cytotoxin, tirapazamine (TPZ).