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The radiosensitizing effects of nicotinamide in combination with carbogen to SCCVII tumors and intestine of mice

โœ Scribed by Koji Ono; Shin-ichirc Masunaga; Mitsuyuki Abe

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
216 KB
Volume
21
Category
Article
ISSN
0360-3016

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The goal of this study was to compare, with a human tumor xenograft, two different strategies for increasing tumor response to fractionated irradiation, namely, oxygenating the hypoxic tumor cells with carbogen and nicotinamide, or killing these cells with the hypoxic cytotoxin, tirapazamine (TPZ).