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Effects of nicotinamide and carbogen on oxygenation in human tumor xenografts measured with luminescense based fiber-optic probes

โœ Scribed by Johan Bussink; Johannes H.A.M Kaanders; Ankie M Strik; Albert J van der Kogel

Book ID
119510754
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
649 KB
Volume
57
Category
Article
ISSN
0167-8140

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โœ Amr El-Said; Douglas Menke; Mary Jo Dorie; J. Martin Brown ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 125 KB ๐Ÿ‘ 2 views

The goal of this study was to compare, with a human tumor xenograft, two different strategies for increasing tumor response to fractionated irradiation, namely, oxygenating the hypoxic tumor cells with carbogen and nicotinamide, or killing these cells with the hypoxic cytotoxin, tirapazamine (TPZ).