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7.001 One-step multiplex PCR for preimplantation genetic diagnosis of Huntington's disease

✍ Scribed by A Peciña; MD Lozano; C Moya; JC Garcí-Lozano; R Carrillo-Vadillo; S Borrego; G Antiñolo


Book ID
119610729
Publisher
Reproductive Healthcare Ltd
Year
2008
Tongue
English
Weight
113 KB
Volume
16
Category
Article
ISSN
1472-6491

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The combination of in vitro fertilization (IVF) with PCR technologies enables diagnosis of single gene defects for preimplantation genetic diagnosis. This has been accomplished by two-step nested PCR, or PEP-PCR followed by nested PCR processes. To improve the detection of single cell genetic defect