Prenatal diagnosis of Huntington's Disease (HD) is controversial. Selective abortion is considered unacceptable by some, since, being a late-onset disorder, any child born carrying the HD mutation might still expect many years of disease-free life. The test result itself has implications for the par
New tools for preimplantation genetic diagnosis of Huntington's disease and their clinical applications
✍ Scribed by Moutou, Céline; Gardes, Nathalie; Viville, Stéphane
- Book ID
- 110025696
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 135 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1018-4813
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📜 SIMILAR VOLUMES
Huntington's disease (HD) is an autosomal dominant disease characterized by motor disturbance, cognitive loss and psychiatric manifestations, starting between the fourth and the fifth decade, followed by death within 10-20 years of onset of the disease. The disease-causing mutation is an expansion o
Cystic fibrosis (CF) is an autosomal recessive disease characterized by obstruction and chronic infections of the respiratory tract and pancreatic insufficiency. The gene was cloned in 1989 and the most frequent mutation was shown to be the delta F508 mutation. During PGD, embryos obtained in vitro